Vertex Pharmaceuticals Incorporated (VRTX) 43rd Annual Cowen Healthcare Conference Transcript

Vertex Prescribed drugs Integrated (NASDAQ:VRTX) forty third Annual Cowen Healthcare Convention March 7, 2023 2:50 PM ET

Firm Individuals

Reshma Kewalramani – President and Chief Government Officer

Charlie Wagner – Chief Monetary Officer

Convention Name Individuals

Phil Nadeau – Cowen

Phil Nadeau

[Call Starts Abruptly] Annual Healthcare Convention. I’m Phil Nadeau, one in all Cowen’s biotech analysts, and it’s my pleasure to do a hearth chat with one of many bellwethers of the trade, Vertex. Blissful to have with us at this time President and CEO, Reshma Kewalramani; and Charlie Wagner, CFO.

Reshma, I’ll hand it to you first for some opening remarks.

Reshma Kewalramani

Certain. Phil, thanks a lot for having us right here. It’s great to see all of you in-person in our residence metropolis of Boston. To start out with, perhaps I’ll simply offer you a bit of little bit of a taste for the place Vertex is at this time, contact on just a few of our packages after which Phil, we will go into any a kind of that you just’d prefer to. It’s an awfully thrilling time for us at Vertex. Having now introduced 4 CF medicines to market and remodeled that illness, the expansion in our CF franchise has remodeled Vertex. We are actually concerned in eight illness areas, together with cystic fibrosis. These are within the clinic at this time and 5 of these illness areas are actually previous the proof-of-concept stage.

A couple of years in the past, we’d have been speaking about rather a lot fewer packages, however we’d have additionally been speaking about rather a lot fewer modalities. At this time, we’re, after all, working in small molecules throughout a variety of these illness areas, however we’re additionally working in gene modifying, with CRISPR/Cas9, with cell remedy in our sort 1 diabetes packages, and with mRNA in RCF packages. As we’ve gone via this progress, we’ve additionally expanded our footprint proper right here in Boston. We’re at our headquarters in Fan